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Synthesis of nitrogen‐containing heterocycles. 3 . Formation and structure of new 1,2,4‐triazole derivatives
Author(s) -
Miyamoto Yoshiko,
Yamazaki Chiji
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260211
Subject(s) - chemistry , aldehyde , ketone , acetic acid , nitrogen , triazole , medicinal chemistry , organic chemistry , catalysis
Treatment of N (3)‐[(2‐cyano‐2‐ethoxycarbonyl)vinyl]amino‐ N (4), N (4)‐dimethylaminomethylenehydrazones of aromatic carbonyl compounds with hot acetic acid resulted in the formation of symmetrical gem‐bis‐(3‐dimethylamino‐1,2,4‐triazol‐1‐yl)methanes, (3‐dimethylamino‐1,2,4‐triazol‐1‐yl)arylmethyl acetates, and (3‐dimethylamino‐1,2,4‐triazol‐1‐yl)alkenes of a gem‐diaryl type depending upon whether the carbonyl compound was aldehyde or ketone.