The synthesis of benzofuroquinolines.  IV . Some halobenzofuro[2,3‐ B ]‐ and [3,2‐ C ]quinoline derivatives | Zendy

Yamaguchi Seiji | Zendy; Tsuzuki Kunihiro | Zendy; Kinoshita Minoru | Zendy; OhHira Yutaka | Zendy; Kawase Yoshiyuki | Zendy

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The synthesis of benzofuroquinolines. IV . Some halobenzofuro[2,3‐ B ]‐ and [3,2‐ C ]quinoline derivatives

Author(s) -

Yamaguchi Seiji,

Tsuzuki Kunihiro,

Kinoshita Minoru,

OhHira Yutaka,

Kawase Yoshiyuki

Publication year - 1989

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570260203

Subject(s) - chemistry , quinoline , halo , stereochemistry , medicinal chemistry , organic chemistry , physics , quantum mechanics , galaxy

Some 8‐ or 9‐halobenzofuro[2,3‐ b ]quinolines ( 1a , 8‐F, 8‐C1, 9‐F, 9‐Cl) and 9‐halobenzofuro[2,3‐ b ]quinoline‐11‐carboxylic acid ( 1b , F, Cl) were synthesized from 6‐ or 7‐halo‐3‐(2‐methoxyphenyl)‐2‐oxo‐1,2‐dihydroquino‐line‐4‐carboxylic acids ( 3 ). And, some 9‐halo‐11(6 H )‐benzofuro[2,3‐ b ]quinolinone ( 8 , F, Cl, Br) and 2‐halo‐6(5 H )‐benzofuro[3,2‐ c ]quinolinone ( 9 , F, Cl, Br) were synthesized from 6‐halo‐4‐hydroxy‐3‐(2‐methoxyphenyl)‐2(1 H )‐quinolinone ( 7 ), and they were converted to the corresponding chlorohalobenzofuroquinolines ( 1c , 9‐F, 9‐C1, 9‐Br, and 2 , F, Cl, Br).

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