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The synthesis and properties of 2‐substituted dihydropyrimidines
Author(s) -
Kashima Choji,
Shimizu Masao,
Omote Yoshimori
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260145
Subject(s) - chemistry , nmr spectra database , proton nmr , medicinal chemistry , organic chemistry , spectral line , physics , astronomy
Various 2‐substituted 1,4‐dihydro‐4,4,6‐trimethyl‐1‐phenylpyrimidines and 1,6‐dihydro‐4,6,6‐trimethylpyrimidines were synthesized independently. For these dihydropyrimidines, the physical data such as the uv, ir, and nmr spectra and the oxidation potential were compared. 2‐Dimethylamino substituted dihydropyrimidine showed the lowest oxidation potential, which expected the similar reducing ability as dihydropyridines.