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Studies on the chemistry of 1,4‐oxazines. 18 . Synthesis of tricyclic 1,4‐benzoxazines via nucleophilic substitution of activated precursors
Author(s) -
Bartsch Herbert,
Erker Thomas,
Neubauer Gustav
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260136
Subject(s) - chemistry , tricyclic , nucleophilic substitution , oxazines , nucleophile , nucleophilic aromatic substitution , stereochemistry , substitution (logic) , organic chemistry , combinatorial chemistry , catalysis , computer science , programming language
Starting from activated benzoxazines 1 and 2 new synthetic pathways to the tricyclic compounds 4, 9, 12 and 16 are described. Reaction of the hydrazides 17a,b with thionylchloride leads to the novel thiatriazolo‐benzoxazines 18a,b .
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