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Amidrazones. 12. Formation of 3‐acylamino‐4,5‐dihydro‐1,1‐dimethyl‐1 H ‐pyrazolium salts by acid‐promoted cyclization of N 3 ‐acylated derivatives of acrylamide dimethylhydrazone and ( E )‐cinnamamide dimethylhydrazone
Author(s) -
Smith Richard F.,
Augustine Brian H.,
Dennis Lisa A.,
Ryan William J.,
Liptak Stephen C.,
Capparelli Brian R.
Publication year - 1989
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570260126
Subject(s) - chemistry , acrylamide , medicinal chemistry , organic chemistry , polymer , copolymer
N 3 ‐Acylated derivatives of acrylamide dimethylhydrazone 3a,b and ( E )‐cinnamamide dimethylhydrazone 3c,d cyclized, on treatment with hydriodic acid or p ‐toluenesulfonic acid, to give 3‐acylamino4,5‐dihydro‐1,1‐dimethyl‐1 H ‐pyrazolium salts 4a‐d .