A three‐step pyridoannelation of carbonyl compounds | Zendy

Chelucci Giorgio | Zendy; Gladiali Serafino | Zendy; Marchetti Mauro | Zendy

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A three‐step pyridoannelation of carbonyl compounds

Author(s) -

Chelucci Giorgio,

Gladiali Serafino,

Marchetti Mauro

Publication year - 1988

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570250630

Subject(s) - chemistry , alkylation , dioxolane , pyridine , scope (computer science) , methylene , elaboration , nucleus , sequence (biology) , organic chemistry , combinatorial chemistry , stereochemistry , catalysis , humanities , biology , programming language , microbiology and biotechnology , philosophy , biochemistry , computer science

The elaboration of a pyridine nucleus onto an α‐methylene carbonyl compound can be accomplished through a three step reaction sequence based on the regiospecific alkylation of N,N ‐dimethylhydrazones with bromoethyl‐1,3‐dioxolane. Scope and limitations of the new method are considered.

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