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A three‐step pyridoannelation of carbonyl compounds
Author(s) -
Chelucci Giorgio,
Gladiali Serafino,
Marchetti Mauro
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250630
Subject(s) - chemistry , alkylation , dioxolane , pyridine , scope (computer science) , methylene , elaboration , nucleus , sequence (biology) , organic chemistry , combinatorial chemistry , stereochemistry , catalysis , humanities , biology , programming language , microbiology and biotechnology , philosophy , biochemistry , computer science
The elaboration of a pyridine nucleus onto an α‐methylene carbonyl compound can be accomplished through a three step reaction sequence based on the regiospecific alkylation of N,N ‐dimethylhydrazones with bromoethyl‐1,3‐dioxolane. Scope and limitations of the new method are considered.

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