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Synthesis of 6,7‐dimethoxypyrimido[4,5‐ b ]‐indoles as potential antihypertensive agents
Author(s) -
Venugopalan B.,
Desai P. D.,
De Souza N. J.
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250607
Subject(s) - chemistry , synthon , stereochemistry , combinatorial chemistry
Using ethyl 5,7‐dimethoxy‐2‐amino‐3‐indolecarboxylate as a synthon, routes are described for the synthesis of the title compounds bearing alkylamino moieties in the 2 and 4‐positions. Some of the compounds displayed antihypertensive activity.