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A facile synthesis of substituted 4,5,6,7‐tetrahydropyrazolo[3,4‐ d ]‐pyrimidine and 1,2,3,4‐tetrahydropyrazolo[1,5‐ a ]triazine derivatives
Author(s) -
Vishwakarma J. N.,
Mofizuddin M.,
Ila H.,
Junjappa H.
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250523
Subject(s) - chemistry , pyrimidine , triazine , formaldehyde , 1,3,5 triazine , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry
Cyclocondensation of 3(5)‐alkylamino‐ and 3(5‐arylaminopyrazoles 1a‐c and 1d‐e with formaldehyde and primary amines affords novel tetrahydropyrazolo[3,4‐ d ]pyrimidines 2 and tetrahydropyrazolo[1,5‐ a ]triazine derivatives 3 respectivley in good yields.
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