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A simple synthesis of 5‐methoxyindole and 5‐methoxy‐2‐oxindole
Author(s) -
Sakamoto Takeshi,
Hosoda Isao,
Kikugawa Yasuo
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250501
Subject(s) - chemistry , oxindole , simple (philosophy) , organic chemistry , combinatorial chemistry , stereochemistry , philosophy , epistemology , catalysis
1‐Methoxy‐ and 1‐hydroxy‐2‐oxindoles rearranged in acidic solution to 5‐substituted 2‐aminophenylacetic acid derivatives which were cyclized to the corresponding 2‐oxindoles with heating. The synthesis of 5‐methoxyindole from 5‐methoxy‐2‐oxindole was also described.