Premium
On 6‐(thenoyl)‐7,8‐dichloro‐4‐oxo‐4 H ‐1‐benzopyran‐2‐carboxylic acid
Author(s) -
Montanari Paola,
Da Re Paolo,
Valenti Piero
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250448
Subject(s) - chemistry , benzopyran , ring (chemistry) , carboxylic acid , pyrone , annulation , stereochemistry , bicyclic molecule , medicinal chemistry , organic chemistry , catalysis
The annulation of the oxyacetic chain of thienylic acid into a γ‐pyrone ring is described. The resulting 6‐(2‐thenoyl)‐7,8‐dichloro‐4‐oxo‐4 H ‐1‐benzopyran‐2‐carboxylic acid retains almost 80% of the diuretic activity of the parent compound.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom