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Condensed heterocycles containing the pyrimidine nucleus
Author(s) -
Santagati Andrea,
Santagati Maria,
Russo Filippo,
Ronsisvalle Giuseppe
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250347
Subject(s) - chemistry , pyrimidine , nucleus , mass spectrum , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , ion , biology , microbiology and biotechnology
Continuing earlier studies designed to obtain derivatives of 1,3,4‐thiadiazolo[3,2‐ a ]pyrimidin‐5‐one and of the isomeric 7‐one of pharmacological interest, some novel compounds 2 and derivatives of 6,7,8,9‐tetrahydro‐5 H ‐1,3,4‐thiadiazolo[2,3‐ b ]quinazolin‐5‐one ( 3 ) were prepared. Derivatives of pyrimido[2,1‐ b ]benzothiazol‐2‐one ( 6 ) and of the isomeric 4‐one derivatives 8 were also synthesized. Structural identification was obtained by 1 H‐nmr, ir and mass spectra.