Synthesis of 5‐phenylpyrrolo[1,2‐ b ][1,2,5]‐triazepin‐2(3 H )‐ones

The synthesis of a series of 5‐phenylpyrrolo[1,2‐ b ][1,2,5]triazepin‐2(3 H )‐ones 1 as potential anxiolytic agents is described. Benzoylation of 1‐phthalimidopyrrole, followed by hydrolysis, gave the 1‐amino‐2‐benzoylpyrroles 3 . These were further functionalized to give the penultimate 1‐aminoacetamido‐2‐benzoylpyrroles 8 and 9 , which were cyclized to the target pyrrolotriazepines 1.