An intramolecular cyclization of 7‐substituted 6‐fluoro‐ 1,8‐naphthyridine and ‐quinoline derivatives | Zendy

Nishimura Yoshiro | Zendy; Minamida Akira | Zendy; Matsumoto JunIchi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

An intramolecular cyclization of 7‐substituted 6‐fluoro‐ 1,8‐naphthyridine and ‐quinoline derivatives

Author(s) -

Nishimura Yoshiro,

Minamida Akira,

Matsumoto JunIchi

Publication year - 1988

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570250224

Subject(s) - chemistry , quinoline , intramolecular force , pyrazine , ring (chemistry) , nucleophile , medicinal chemistry , combinatorial chemistry , stereochemistry , organic chemistry , catalysis

A synthesis of 1,4‐oxazine and pyrazine ring systems by an intramolecular cyclization of 7‐substituted 1‐ethyl‐6‐fluoro‐1,4‐dihydro‐4‐oxo‐1,8‐naphthyridine and ‐quinoline derivatives having a nitrogen or oxygen nucleophilic site in the C‐7 appendage was studied. The in vitro antibacterial activities of compounds prepared by this method were tested.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research