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Acid‐catalyzed reactions of 3‐(α‐hydroxybenzyl)pyrazolo[1,5‐ a ]pyridines
Author(s) -
Miki Yasuyoshi,
Tomii Osamu,
Nakao Hayami,
Kubo Mayumi,
Hachiken Hiroko,
Takemura Shoji,
Ikeda Masazumi
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250155
Subject(s) - chemistry , trifluoroacetic acid , dichloromethane , catalysis , medicinal chemistry , organic chemistry , solvent
Treatment of 3‐(or‐hydroxybenzyl)pyrazolo[1,5‐a]pyridines with trifluoroacetic acid in dichloromethane resulted in the formation of pyrazolo[1,5‐a]pyridines, bis[α‐(pyrazolo[1,5‐ a ]pyrid‐3‐yl)benzyl] ethers, and phenylbis(pyrazolo[1,5‐a]pyrid‐3‐yl)methanes, depending upon the presence or absence of the substituents at the 2‐ and/or 4‐positions and the reaction conditions employed.

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