Pyridazines.  XXXV  . Preparation of some novel pyrimido[4,5‐ c ]pyridazine derivatives from 3‐alkylamino‐ and 3‐arylamino‐4‐pyridazinecarboxamides | Zendy

Haider Norbert | Zendy; Heinisch Gottfried | Zendy; Laßnigg Doris | Zendy

Premium

Pyridazines. XXXV . Preparation of some novel pyrimido[4,5‐ c ]pyridazine derivatives from 3‐alkylamino‐ and 3‐arylamino‐4‐pyridazinecarboxamides

Author(s) -

Haider Norbert,

Heinisch Gottfried,

Laßnigg Doris

Publication year - 1988

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570250117

Subject(s) - pyridazine , chemistry , combinatorial chemistry , stereochemistry , medicinal chemistry

Facile syntheses of pyrimido[4,5‐ c ]pyridazine‐5,7(6 H ,8 H )diones 4 , pyrimido[4,5‐c]pyridazin‐5(8 H )‐ones 7–10 , and dihydropyrimido[4,5‐ c ]pyridazin‐5(6 H )ones 5,6 starting from 3‐chloro‐4‐pyridazinecarbonitrile 1 via aminocarbonitriles 2 and aminocarboxamides 3 are described. In addition, a convenient access to the new aminopyridazinecarbonitrile 11 from the chloronitrile 1, employing the tetrazolo[1,5‐ b ]pyridazine 12 as the key intermediate, is reported.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research