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On the oxidizability of 1‐methyl‐1,2,3,4‐tetrahydropyrimido[1,2‐ a ]indole‐10‐carboxaldehyde and its crystal structure
Author(s) -
Andreani Aldo,
Greci Lucedio,
Tosi Giorgio,
Sgarabotto Paolo,
Ugozzoli Franco
Publication year - 1988
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570250104
Subject(s) - indole test , chemistry , ring (chemistry) , electrochemistry , nitrogen , crystal structure , crystal (programming language) , stereochemistry , medicinal chemistry , organic chemistry , electrode , computer science , programming language
The study of the molecular geometry of 1‐methyl‐1,2,3,4‐tetrahydropyrimido[1,2‐ a ]indole‐10‐carboxaldehyde as determined by X‐ray analysis and the electrochemical properties of that compound are reported. These are compared with those of a number of indole‐3‐carboxaldehyde, differently substituted at 1 and 2 position. This was done in order to understand the unsuccessful attempts to convert the title compound into the corresponding acid. The result indicate that this anomalous behaviour may be attributed to easy oxidizability of the pyrimido ring nitrogen.