A new method for the synthesis of novel 3‐substituted 4‐amino‐8‐ethoxycarbonylpyrazolo[5,1‐ c ][1,2,4]triazines and pyrazolo[1′,5′:3,4][1,2,4]triazino[5,6‐ b ][1,5]benzodiazepines | Zendy

Kurasawa Yoshihisa | Zendy; Okamoto Yoshihisa | Zendy; Takada Atsushi | Zendy

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A new method for the synthesis of novel 3‐substituted 4‐amino‐8‐ethoxycarbonylpyrazolo[5,1‐ c ][1,2,4]triazines and pyrazolo[1′,5′:3,4][1,2,4]triazino[5,6‐ b ][1,5]benzodiazepines

Author(s) -

Kurasawa Yoshihisa,

Okamoto Yoshihisa,

Takada Atsushi

Publication year - 1987

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570240656

Subject(s) - malononitrile , chemistry , ethyl cyanoacetate , salt (chemistry) , pyrazole , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis

Novel 3‐substituted 4‐amino‐8‐ethoxycarbonylpyrazolo[5,1‐ c ][1,2,4]triazines 7,8 were synthesized by the reactions of malononitrile and ethyl cyanoacetate with the pyrazole‐5‐diazonium salt 3 . Moreover, compounds 7,8 were converted into the pyrazolo[1′,5′:3,4][1,2,4]triazino[5,6‐ b ][1,5]benzodiazepines 9, 10 .

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