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Synthesis and antifungal activity of some allylamine derivatives
Author(s) -
Bandiera Tiziano,
Albini Franca Mari,
Albini Enrico
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240619
Subject(s) - allylamine , chemistry , antifungal , yield (engineering) , organic chemistry , microbiology and biotechnology , materials science , polyelectrolyte , metallurgy , biology , polymer
Benzo‐ and mesitonitrile oxides react with allylamine to yield 5‐aminomethyl‐2‐isoxazolines and open‐chain N ‐substituted amidoximes. The allylamine derivatives were evaluated as potential antifungal and antibacterial agents. The N ‐allylbenzamidoxime 2a was found to be only moderately active against dermatophytes.