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A facile synthesis of the 1,3‐dithiolo[4,5‐ b ]pyridine ring system via pyridylthiocyanates
Author(s) -
Chen Ted K.,
Flowers William T.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240613
Subject(s) - chemistry , pyridine , yield (engineering) , ring (chemistry) , thio , medicinal chemistry , stereochemistry , organic chemistry , materials science , metallurgy
2‐Chloro‐3‐thiocyanatopyridine reacted with thioacetic acid and thiobenzoic acid to yield 2‐acetylimino‐1,3‐dithiolo[4,5‐ b ]pyridine and 2‐benzoylimino‐1,3‐dithiolo[4,5‐ b ]pyridine respectively. 2,5,6‐Trihalo‐3‐thiocyanatopyridine under the same conditions gave only the corresponding 3‐ S ‐acetyl‐3‐thio or 3‐ S ‐benzoyl‐3‐thiopyridine.