Reaction of  N,N ‐dimethylazidochloromethyleniminium chloride (azidophosgeniminium chloride) with 1,3‐dimethyl‐4‐aminouracils. A new “one pot” synthesis of 3‐aryl‐(and 3‐alkyl)‐4,6‐dimethyl‐5,7‐dioxo‐1,2,3‐triazolo[4,5‐ d ]pyrimidines (8‐azatheophyllines)  via  a diazo group transfer process | Zendy

Kokel Bruno | Zendy; Boussouira Nadia | Zendy

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Reaction of N,N ‐dimethylazidochloromethyleniminium chloride (azidophosgeniminium chloride) with 1,3‐dimethyl‐4‐aminouracils. A new “one pot” synthesis of 3‐aryl‐(and 3‐alkyl)‐4,6‐dimethyl‐5,7‐dioxo‐1,2,3‐triazolo[4,5‐ d ]pyrimidines (8‐azatheophyllines) via a diazo group transfer process

Author(s) -

Kokel Bruno,

Boussouira Nadia

Publication year - 1987

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570240601

Subject(s) - chemistry , alkyl , diazo , aryl , yield (engineering) , chloride , medicinal chemistry , organic chemistry , materials science , metallurgy

N,N ‐Dimethylazidochloromethyleniminium chloride (azidophosgeniminium chloride) ( 1 ) reacts by diazo group transfer with 1,3‐dimethyl‐4‐aryl‐(and alkyl)aminouracils 4 to give, under mild “one pot” reaction conditions, a very good yield of 3‐aryl‐(and 3‐alkyl)‐4,6‐dimethyl‐5,7‐dioxo‐1,2,3‐triazolo[4,5‐ d ]pyrimidines (8‐azatheophyllines) 8 . That reaction proceeds, very likely, through formation of non‐isolated 4‐imino‐5‐diazouracils 6 .

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