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Studies on decarboxylation reactions. Part 5 . Micellar catalysis and mixed solvents effects on the decarboxylation of some N ‐alkyl‐ or N ‐aryl‐substituted 5‐amino‐1,3,4‐oxadiazole‐2‐carboxylic acids
Author(s) -
Noto Renato,
Buscemi Silvestre,
Werber Giuseppe,
Spinelli Domenico
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240545
Subject(s) - decarboxylation , chemistry , aryl , alkyl , micelle , reactivity (psychology) , catalysis , amino acid , medicinal chemistry , organic chemistry , aqueous solution , biochemistry , medicine , alternative medicine , pathology
The effect of micelles and mixed solvents on the decarboxylation of some N ‐alkyl‐ or N ‐aryl‐substituted 5‐amino‐1,3,4‐oxadiazole‐2‐carboxylic acids has been studied. The data support the unimolecular decarboxylation mechanism proposed by us. Moreover, they show that mixed solvents and micelles have different effects on reactivity of the amino acids under study.