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A convenient synthesis of novel pyridazino[3,4‐b]quinoxalines
Author(s) -
Kurasawa Yoshihisa,
Arai Harumi,
Arai Kiyoko,
Satoh Atsushi,
Ninomiya Satoyuki,
Okamoto Yoshihisa,
Takada Atsushi
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240455
Subject(s) - chemistry , combinatorial chemistry , stereochemistry
Novel 4‐chlorophenylhydrazono‐3‐oxo‐1,2,3,4‐tetrahydropyridazino[3,4‐ b ]quinoxalines 10a‐c were synthesized by the cyclization of the α‐hydrazonohydrazides 8a‐c. The chlorination of 10a with phosphoryl chloride afforded 3‐chloro‐4‐[2‐( o ‐chlorophenyl)hydrazino]pyridazino[3,4‐ b ]quinoxaline 12.
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