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Heterocycles. Part XII. Synthesis of new benzo[6,7]cyclohepta[1,2‐ d ]pyrimidine
Author(s) -
ElRayyes N. R.,
Ramadan H. M.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240442
Subject(s) - chemistry , amidine , guanidine , hydrochloride , condensation , pyrimidine , medicinal chemistry , stereochemistry , organic chemistry , physics , thermodynamics
Selected 2‐arylidene‐1‐benzosuberones I were condensed with guanidine hydrochloride to give the corresponding substituted 2‐aminopyrimidines II and III respectively. Condensation of chalcones I with benz‐amidine hydrochloride revealed the formation of the corresponding substituted 2‐phenylpyrimidines IV. The structure of all products was substantiated by chemical and spectroscopic methods.