Premium
Studies on the synthesis and interconversion of isomeric triazolothienopyrimidines. Part III. Cyclization reactions of 2‐amino‐3‐(1 H ‐1,2,4‐triazol‐3‐yl)thiophenes
Author(s) -
Shishoo C. J.,
Devani M. B.,
Ullas G. V.,
Ananthan S.,
Bhadti V. S.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240439
Subject(s) - chemistry , cleavage (geology) , stereochemistry , hydrolysis , medicinal chemistry , combinatorial chemistry , organic chemistry , geotechnical engineering , fracture (geology) , engineering
Isolation of 2‐amino‐3‐(1 H ‐1,2,4‐triazol‐3‐yl)thiophenes in the hydrolytic cleavage reactions of isomeric triazolothienopyrimidines is reported. The 2‐amino‐3‐triazolylthiophenes on reaction with one carbon donors were found to cyclize to 1,2,4‐triazolo[1,5‐ c ]thienopyrimidines, exclusively.