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Synthesis of 3‐phenylpyrroles by hydride reduction of 4‐hydroxypyrrolidin‐2‐ones
Author(s) -
Hasegawa Tadashi,
Nakamura Fuki,
Moribe JunIchi,
Yoshioka Michikazu
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240355
Subject(s) - chemistry , aluminum hydride , hydride , reduction (mathematics) , lithium (medication) , lithium hydride , lithium aluminium hydride , medicinal chemistry , combinatorial chemistry , organic chemistry , ion , hydrogen , ionic bonding , geometry , mathematics , medicine , methoxide , endocrinology
3‐Phenylpyrroles 2 were easily prepared in good yields by hydride reduction of 4‐hydroxypyrrolidin‐2‐ones 1 , which have been prepared in high yields from the photoreaction of N,N ‐dialkylbenzoylacetamides, with lithium aluminum hydride.