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Reduction of α,β‐unsaturated nitroalkenes with borane and borohydrides. A convenient route to 3‐nitro‐, 3‐hydroxylamino‐, and 3‐amino‐2h‐1‐benzopyran derivatives
Author(s) -
Varma Rajender S.,
Gai YuanZhu,
Kabalka George W.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240343
Subject(s) - chemistry , borane , nitro , borohydride , reduction (mathematics) , selective reduction , benzopyran , medicinal chemistry , catalysis , combinatorial chemistry , organic chemistry , alkyl , geometry , mathematics
Abstract The borohydride catalyzed borane reduction of 3‐nitrochromenes provided a facile route to a variety of 3‐hydroxylamino‐ 5 and 3‐amino‐2 H ‐1‐benzopyranes 6. Reduction with methoxyborohydride species, on the other hand, provided 3‐nitrochromans 2,4.