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Reaction of 4‐acylaminomethylpyridine N‐oxides with phenylbutazone in the presence of acetic anhydride
Author(s) -
Braña M. F.,
Castellano J. M.,
Redondo M. C.,
Esplugues J.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240339
Subject(s) - chemistry , acetic anhydride , phenylbutazone , organic chemistry , anticonvulsant , catalysis , pharmacology , epilepsy , medicine , neuroscience , biology
Reaction of 4‐acylaminomethylpyridine N ‐oxides with phenylbutazone in the presence of acetic anhydride is described. In the pharmacological screening one compound shows an interesting anticonvulsant activity.