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Aroylnitrile oxide cyclizations. 2. Synthesis of (3‐aroylisoxazol‐5‐yl)alkanoic acids
Author(s) -
Tegeler John J.,
Diamond Craig J.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240331
Subject(s) - chemistry , oxide , organic chemistry , medicinal chemistry
Intermolecular cyclization of 1,3‐dipolar aroylnitrile oxides to terminal alkynols followed by phase transfer catalyzed oxidation provided a short, convenient route to several novel (3‐aroylisoxazol‐5‐yl)alkanoic acids.
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