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Heterocycles. Part X . Synthesis of new pyrimidine systems
Author(s) -
ElRayyes N. R.,
Ramadan H. M.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240310
Subject(s) - chemistry , thiourea , pyrimidine , urea , condensation , aryl , organic chemistry , medicinal chemistry , stereochemistry , physics , alkyl , thermodynamics
Selected aryl aldehydes I were reacted with 1‐benzosuberone to give the corresponding 2‐arylidene‐1‐ben‐zosuberones II. Condensation of these chalcones with urea and thiourea revealed the formation of the corresponding substituted pyrimidin‐2‐ones III , and pyrimidine‐2‐thiones IV respectively. The structure of all products was substantiated by chemical and spectral methods.