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A novel acyclic addition of ketenes to oxazoles/oxazolines
Author(s) -
Nyce P.,
Puar M. S.,
Gala D.,
Jaret R. S.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240239
Subject(s) - chemistry , combinatorial chemistry , organic chemistry
The addition of n ‐butyryl chloride (1) to 5‐phenyloxazole (6) or 4,5‐dihydro‐5‐methyl‐4‐[(4′‐methylphenyl)‐sulfonyl]oxazole (8) in the presence of triethylamine lead to 1‐(5′‐phenyloxazol‐2′‐yl)‐1‐buten‐1‐yl butanoate (7) and 1‐(5′‐methyl‐4′‐[4″‐methylphenylsulfonyl]4′,5′‐dihydrooxazol‐2′‐yl)‐1‐buten‐1‐yl butanoate (9) , respectively.