Premium
Synthesis of some hydroxy and methoxymethyl derivations of 1 H ‐pyrazolo[5,1‐ c ]‐1,2,4‐triazoles
Author(s) -
Goddard John D.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240157
Subject(s) - chemistry , cyclopropane , electrophile , hydroxide , hydroxylation , medicinal chemistry , organic chemistry , stereochemistry , ring (chemistry) , catalysis , enzyme
Electrophilic hydroxylation of a pyrazolotriazole with a mixture of trifuoroacetic attack of methanolic hydroxide ion on a dichloropyrazolotriazole gave a 6‐methoxymethylpyrazolotriazole by a mechanism involveing a cyclopropane intermediate.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom