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Spirolactones of xanthene. III. Formation and molecular structure of novel spirolactones of xanthene and dibenzo[c,h]xanthene
Author(s) -
Kimura Michio
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240155
Subject(s) - xanthene , chemistry , nitrobenzene , toluene , molecule , phenol , xylene , solvent , oxalic acid , organic chemistry , medicinal chemistry , catalysis
The reaction of 1‐naphthol or phenol derivatives with oxalic and sulfuric acids yielded novel spirolactones. Eight examples ( 2a‐h ) were synthesized by this reaction. The structures of the spirolactones were established from spectral evidence and the X‐ray diffraction studies. Some of the spirolactones form the solvates with the aromatic solvent molecules, such as toluene, xylene and nitrobenzene, and the structure of the nitrobenzene solvate of 2a was determined by the X‐ray analysis.