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New reactions of deoxyvasicinone. Part 6
Author(s) -
Dunn A. D.,
Kinnear K. I.,
Norrie R.,
Ringan N.,
Martin D.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240133
Subject(s) - chemistry , methylene , dehydration , hydroxymethyl , derivative (finance) , stereochemistry , dehydration reaction , medicinal chemistry , biochemistry , financial economics , economics
Several acylated derivatives of deoxyvasicinone 1 and its analogues were shown to exist as enols. The 3‐hydroxymethyl derivative of 1 was shown to undergo rapid dehydration and products derived from an intermediate 3‐methylene compound were obtained. Novel oxazepino analogues of 1 are reported.