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A new route to 6‐azachromones. An improved synthesis of 2‐azaxanthone
Author(s) -
Cordonnier Guy,
Sliwa Henri
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240123
Subject(s) - chemistry , morpholine , enamine , yield (engineering) , condensation , organic chemistry , combinatorial chemistry , stereochemistry , catalysis , materials science , physics , metallurgy , thermodynamics
Condensation of the morpholine enamine of 1‐benzyl‐4‐piperidone with β‐ketoesters yielded 6‐azatetrahy‐drochromones which were debenzylated and aromatized to 6‐azachromones; 2‐azaxanthone has been thus obtained with an improved yield as compared to previous syntheses.