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The condensation products of 2,3,6‐trisubstituted‐1,4‐naphthoquinones with 2‐aminothiophenol
Author(s) -
Kang W. B.,
Nan'Ya Seiko,
Yamaguchi Yasushi,
Maekawa EturǑ,
Ueno Yoshio
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240119
Subject(s) - chemistry , condensation , aniline , phenothiazine , halogenation , condensation reaction , organic chemistry , medicinal chemistry , combinatorial chemistry , catalysis , medicine , physics , pharmacology , thermodynamics
The 2,6‐disubstituted‐, 3,6‐disubstituted‐5 H ‐benzo[ a ]phenothiazin‐5‐one derivatives and 7‐substituted‐benzo[ a ] [1,4]benzothiazino[3,2‐ a ]phenothiazine derivatives were prepared by the condensation of 2,3,6‐trisubstituted‐1,4‐naphthoquinones with 2‐aminothiophenol. The resulting compounds were subjected to reduction, dehalogenation and condensation with aniline. Some of the condensation intermediates were isolated and the reaction mechanism was also investigated.