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β‐Angelica lactone epoxide: Chemical behaviour and some synthetic applications
Author(s) -
Ortuño R. M.,
Cardellach J.,
Font J.
Publication year - 1987
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570240117
Subject(s) - chemistry , epoxide , lactone , nucleophile , derivative (finance) , organic chemistry , epoxy , combinatorial chemistry , catalysis , financial economics , economics
A new epoxy derivative of ß‐angelica lactone has been synthesized. Its chemical behaviour towards nucleophiles has been explored in order to prepare natural products with a trisubstituted ß‐hydroxy‐γ‐methylbutyrolactone‐type constitution. Thus, some potential precursors have been obtained and an efficient and stereo‐controlled synthesis of (±)‐blastmycinone is reported.