Conversion of 4‐amino‐1 H ‐1,5‐benzodiazepine‐3‐carbonitrile to pyrazolo[3,4‐ d ]pyrimidines, pyrimido[1,6‐ a ]benzimidazole, and pyrazolo[3′,4′:4,5]pyrimido[1,6‐ a ]benzimidazoles | Zendy

Okamoto Yoshihisa | Zendy; Togo Isao | Zendy; Kurasawa Yoshihisa | Zendy; Takagi Kaname | Zendy

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Conversion of 4‐amino‐1 H ‐1,5‐benzodiazepine‐3‐carbonitrile to pyrazolo[3,4‐ d ]pyrimidines, pyrimido[1,6‐ a ]benzimidazole, and pyrazolo[3′,4′:4,5]pyrimido[1,6‐ a ]benzimidazoles

Author(s) -

Okamoto Yoshihisa,

Togo Isao,

Kurasawa Yoshihisa,

Takagi Kaname

Publication year - 1986

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570230644

Subject(s) - chemistry , benzimidazole , benzodiazepine , stereochemistry , medicinal chemistry , combinatorial chemistry , organic chemistry , biochemistry , receptor

The reactions of multifunctional compounds 2a, b, c, 3a, b and 4a, b which were readily obtained from 4‐amino‐1 H ‐1,5‐benzodiazepine‐3‐carbonitrile 1 with orthoesters are described, and derivatives of pyrazolo‐[3,4‐ d ]pyrimidines 5 , pyrimido[1,6‐ a ]benzimidazole 9 , and pyrazolo[3′,4′:4,5]pyrimido[1,6‐ a ]benzimidazole 10 are synthesized.

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