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A facile synthesis of 1‐aryl‐3‐heteroaryl‐1 H ‐pyrazolo[3,4‐ b ]quinoxalines and related compounds with antifungal activity Synthesis of 1‐Aryl‐3‐heteroaryl‐1 H ‐pyrazolo[3,4‐ b ]quinoxalines
Author(s) -
Kurasawa Yoshihisa,
Muramatsu Muneto,
Yamazaki Kaoru,
Tajima Setsuko,
Okamoto Yoshihisa,
Takada Atsushi
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230527
Subject(s) - chemistry , aryl , antifungal , hydrazone , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , alkyl , medicine , dermatology
The novel 1 H ‐pyrazolo[3,4‐ b ]quinoxalines (flavazoles) 9–15 were synthesized from 3‐methoxycarbonylmethylene‐2‐oxo‐1,2,3,4‐tetrahydroquinoxaline 6 via a convenient hydrazone synthesis, and these flavazoles were clarified to have the antifungal activity.
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