Synthesis and  in vitro  antimicrobial and antifungal properties of some novel 1,3,4‐thiadiazole and  s ‐triazolo[3,4‐ b ][1,3,4]thiadiazole derivatives | Zendy

Omar A.Mohsen M. E. | Zendy; Aboulwafa Omaima M. | Zendy

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Synthesis and in vitro antimicrobial and antifungal properties of some novel 1,3,4‐thiadiazole and s ‐triazolo[3,4‐ b ][1,3,4]thiadiazole derivatives

Author(s) -

Omar A.Mohsen M. E.,

Aboulwafa Omaima M.

Publication year - 1986

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570230514

Subject(s) - thiadiazoles , chemistry , antimicrobial , candida albicans , antifungal , in vitro , staphylococcus aureus , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , microbiology and biotechnology , bacteria , biochemistry , genetics , biology

A novel series of 2‐arylthiocarbamoylhydrazino‐5‐phenyl‐1,3,4‐thiadiazoles III‐VII was synthesized and cyclodesulfurized into the corresponding 3‐arylamino‐6‐phenyl‐ s ‐triazolo[3,4‐ b ][1,3,4]thiadiazoles VIII‐XII with DCCD. Some of the products were found to be only moderately active against Staphylococcus aureus and Candida albicans .

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