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Synthesis of 2‐substituted benzimidazole‐5‐carbamates as potential antifilarial agents
Author(s) -
Ram Siya,
Wise Dean S.,
Townsend LeRoy B.
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230430
Subject(s) - benzimidazole , chemistry , combinatorial chemistry , pharmacology , organic chemistry , medicine
A number of 2,5‐disubstituted benzimidazoles have been prepared from 2‐benzyl‐5‐nitrobenzimidazole ( 5 ) and 2‐ p ‐fluorobenzyl‐5‐nitrobenzimidazole ( 6 ), and evaluated as potential antifilarial agents. None of the compounds prepared in this study have demonstrated any significant antifilarial activity.