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Synthesis of the angular furanoxanthone, deoxydehydropsorospermin methyl ether (5,10‐dimethoxy‐2‐isopropenyl‐6 H ‐furo[2,3‐ c ]xanthen‐6‐one)
Author(s) -
Scannell Ralph T.,
Stevenson Robert
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230338
Subject(s) - chemistry , ether , organic chemistry , medicinal chemistry , stereochemistry
The angular isopropenylfuranoxanthone heterocyclic system, on which the anti‐leukemic natural product psorospermin is based, is synthesized by the reaction of cuprous isopropenylacetylide with 4‐bromo‐1,5‐dimethoxy‐3‐hydroxyxanthone.