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Polycyclic N ‐hetero compounds. XX. Synthesis of 11,13,15‐triazasteroid with an alkyl group in the d‐ring and an investigation of its antidepressive activity
Author(s) -
Hirota Takashi,
Kawanishi Keiko,
Sasaki Kenji,
Namba Tetsuto,
Iwadoh Akimasa,
Hayakawa Shohei
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230309
Subject(s) - chemistry , alkyl , ring (chemistry) , stereochemistry , group (periodic table) , medicinal chemistry , organic chemistry
11,13,15‐Triazasteroidal skeleton with an alkyl group in the D‐ring was synthesized and it was screened for antidepressive activity. Compounds VIIId and XIIa exhibited antireserpine action.