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Chemical reactions of cycloalkanespirohydantoins. Part 2. Synthesis of new 4‐hydroxyimidazolidinone N 3 ‐substituted from cycloalkanespirohydantoins
Author(s) -
Salazar Loreto,
Rubido Julia,
Espada Modesta,
Pedregal Carmen,
Trigo Gregorio,
Elguero José
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230234
Subject(s) - chemistry , organic chemistry , combinatorial chemistry , stereochemistry
N 3 ‐Substituted hydantoins have been to undergo lithium aluminum hydride reduction (THF, room temperature, 5 hours) to give 4‐hydroxy‐2‐imidazolidinones in good yields.