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Novel syntheses of 3‐cyano‐3,4‐dihydroquinolin‐2(1 H )‐one and derivatives of 2,3‐dicarbomethoxy‐2‐hydroxycyclopenta[ b ]quinoline
Author(s) -
Bhat Balkrishen,
Bhaduri Amiya Prasad
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230219
Subject(s) - chemistry , quinoline , medicinal chemistry , combinatorial chemistry , organic chemistry , stereochemistry
A facile solid phase conversion of 2‐chloro‐3‐cyano‐4‐substituted‐1,4‐dihydroquinolines to 3‐cyano‐4‐substituted‐3,4‐dihydroquinolin‐2(1 H )‐ones in almost quantitative yields and a novel synthesis of 2,3‐dicarbomethoxy‐2‐hydroxycyclopenta[ b ]quinoline are described.