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Asymmetric alkaloid synthesis from ( S )‐pyroglutamic acid. I. Synthesis of ( S )‐5‐ethyl‐2‐pyrrolidinone
Author(s) -
Marco José L.
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230160
Subject(s) - chemistry , pyroglutamic acid , yield (engineering) , alkaloid , stereochemistry , ethyl ester , pyrrolidinones , organic chemistry , amino acid , biochemistry , materials science , metallurgy
From ( S )‐pyroglutamic acid ( 1 ) the asymmetric synthesis of ( S )‐5‐ethyl‐2‐pyrrolidinone ( 5 ) in 30% yield is described.