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A facile synthesis of novel 1‐aryl‐1 H ‐pyrazolo[3,4‐ b ]quinoxalines
Author(s) -
Kurasawa Yoshihisa,
Yamazaki Kaoru,
Tajima Setsuko,
Okamoto Yoshihisa,
Takada Atsushi
Publication year - 1986
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570230158
Subject(s) - chemistry , aryl , quinoxaline , base (topology) , dimethylformamide , medicinal chemistry , chloride , phosphoryl chloride , organic chemistry , solvent , alkyl , mathematical analysis , mathematics
The reactions of 3‐methyl‐2‐oxo‐1,2‐dihydroquinoxaline 3 with chlorophenyl diazonium salts afforded the hydrazones 4a‐c , whose chlorinations with phosphoryl chloride gave the dichlorides 5a‐c . Refluxing of the dichlorides 5a‐c and base in N,N ‐dimethylformamide provided the 1‐aryl‐1 H ‐pyrazolo[3,4‐ b ]quinoxalines 6a‐c .