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On the synthesis of geometric isomers of 2‐methyl (or phenyl)‐4‐[α‐arylethylidene]‐5(4 H )‐oxazolones
Author(s) -
Cativiela C.,
De Villegas M. D. Diaz,
Meléndez E.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220637
Subject(s) - chemistry , diazomethane , isomerization , benzene , condensation , hydrogen bromide , bromide , medicinal chemistry , organic chemistry , stereochemistry , catalysis , physics , bromine , thermodynamics
Several Z ‐2‐methyl(or phenyl)‐4‐[α‐arylethylidene]‐5(4 H )‐oxazolones 3Z, 4Z were prepared. The results obtained were compared by diazomethane insertion and condensation procedure. In order to synthesize E ‐2‐phenyl‐4‐[α‐arylethylidene]‐5(4 H )‐oxazolones 4E hydrogen bromide isomerization in dry benzene was used.