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Synthesis of N 4 ‐(5‐methoxy‐7‐benzofuranyl)‐1,4‐pentanediamine, an oxygen isostere of primaquine
Author(s) -
Johnson Judith L.,
Werbel Leslie M.
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220549
Subject(s) - isostere , chemistry , primaquine , oxygen , bicyclic molecule , medicinal chemistry , stereochemistry , organic chemistry , chloroquine , malaria , immunology , biology
N 4 ‐(5‐Methoxy‐7‐benzofuranyl)‐1,4‐pentanediamine, an oxygen isostere of primaquine was synthesized and found devoid of antimalarial activity.