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Synthesis and properties of some 7‐dimethylamino‐1,4‐benzoxazin‐2‐ones
Author(s) -
Le Bris MarieThérèse
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220526
Subject(s) - chemistry , substituent , hydrochloric acid , organic chemistry , fluorescence , quantum mechanics , physics
Abstract The synthesis of the 7‐dimethylamino‐1,4‐benzoxazin‐2‐ones ( 5 ), fluorescent dyes, by condensing α‐keto‐acids with 2‐amino‐5‐dimethylaminophenol is described. When the 3‐substituent is a methyl group, these compounds can be further condensed with aromatic aldehydes to provide the styryl dyes ( 6 ). These products are easily opened by hydrochloric acid in ethanolic solution to afford the corresponding benzalketoacid ethyl esters ( 7 ).