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Novel synthesis of pyrazole and pyrazoline derivatives
Author(s) -
Matsumura Noboru,
Kunugihara Akira,
Yoneda Shigeo
Publication year - 1985
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570220503
Subject(s) - chemistry , acetophenone , pyrazole , pyrazoline , phenacyl , thionyl chloride , organic chemistry , chloride , medicinal chemistry , catalysis
The 1,4‐dianion of acetophenone N ‐ethoxycarbonylhydrazone reacts with carbonyl compounds such as esters, acyl chlorides, amides and α‐haloketones such as phenacyl chloride, 1‐chloroacetone, 1,3‐dichloroacetone, to produce pyrazole and pyrazoline derivatives in good yields, respectively.
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